4.5 Article

Study on the Treatment of Acute Thallium Poisoning

Journal

AMERICAN JOURNAL OF THE MEDICAL SCIENCES
Volume 347, Issue 5, Pages 377-381

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1097/MAJ.0b013e318298de9c

Keywords

Acute thallium poisoning; Prussian blue; Blood purification therapies; Hemoperfusion

Funding

  1. Youth Foundation of Zhengzhou University [2011007]

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Background:Acute thallium poisoning rarely occurs but is a serious and even fatal medical condition. Currently, patients with acute thallium poisoning are usually treated with Prussian blue and blood purification therapy. However, there are few studies about these treatments for acute thallium poisoning.Methods:Nine patients with acute thallium poisoning from 1 family were treated successfully with Prussian blue and different types of blood purification therapies and analyzed.Results:Prussian blue combined with sequential hemodialysis, hemoperfusion and/or continuous veno-venous hemofiltration were effective for the treatment of patients with acute thallium poisoning, even after delayed diagnosis.Conclusions:Blood purification therapies help in the clearance of thallium in those with acute thallium poisoning. Prussian blue treatment may do the benefit during this process.

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