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Hyperglycemia in Nondiabetic Patients Presenting With Acute Myocardial Infarction

Journal

AMERICAN JOURNAL OF THE MEDICAL SCIENCES
Volume 343, Issue 4, Pages 321-326

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1097/MAJ.0b013e31822fb423

Keywords

Hyperglycemia; Nondiabetic; Acute myocardial infarction; Diabetes mellitus

Funding

  1. NCATS NIH HHS [UL1 TR001445] Funding Source: Medline

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Hyperglycemia is common in nondiabetic patients with acute myocardial infarction (AMI). Elevated blood glucose level may reflect a response to stress, an underlying abnormal glucometabolic state or both. Regardless of mechanism, hyperglycemia complicating AMI is associated with an inflammatory and prothrombotic state, depressed myocardial contractility and increased short- and long-term mortality. Studies are needed to define optimal monitoring and management of hyperglycemia in nondiabetic patients with AMI.

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