Journal
TETRAHEDRON LETTERS
Volume 48, Issue 49, Pages 8735-8738Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.10.008
Keywords
aza-Michael reaction; polystyrenesulfonic acid (PSSA); aqueous medium; microwave irradiation
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An efficient and environmentally benign tandem bis-aza-Michael addition of amines catalyzed by polystyrenesulfonic acid (PSSA) is described. This operationally simple high yielding microwave assisted synthetic protocol proceeded in water in the absence of any organic solvent. (c) 2007 Elsevier Ltd. All rights reserved.
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