4.4 Article

Preparation of unsaturated aminonitriles from the aza-Morita-Baylis-Hillman reactions of aldimines with penta-2,4-dienenitrile

Journal

SYNLETT
Volume -, Issue 19, Pages 2995-2998

Publisher

GEORG THIEME VERLAG KG
DOI: 10.1055/s-2007-990886

Keywords

aza-Morita-Baylis-Hillman reaction; penta-2,4-dienenitrile; conjugated diene; N-(phenylsulfonyl)aldimines; unsaturated; aminonitriles

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N-(Phenylsulfonyl)aldinlines undergo facile aza-Morita-Baylis-Hillman reactions with penta-2,4-dienenitrile in anhydrous DMF in the presence of catalytic 3-hydroxyquinuclidine and methanol to afford the corresponding unsaturated aminonitriles.

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