4.8 Article

Total synthesis and antibacterial properties of carbaplatensimycin

Journal

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 129, Issue 48, Pages 14850-+

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ja076126e

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The chemical synthesis and biological evaluation of carbaplatensimycin, the carbon analogue of the recently reported antibiotic platensimycin has been accomplished. Carbaplatensimycin exhibited similar potency to the natural product as an antibacterial agent against a variety of strains, including methicilin- and vancomycin-resistant bacteria.

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