4.8 Article

Catalytic enantioselective addition of arylboronic acids to N-Boc imines generated in situ

Journal

ORGANIC LETTERS
Volume 9, Issue 25, Pages 5155-5157

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol702045w

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The rhodium-catalyzed addition of arylboronic acids to N-Boc imines generated in situ from stable and easily prepared alpha-carbamoyl sulfones has been developed. High enantioselectivities are observed for additions of arylboronic acids with a variety of steric and electronic properties.

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