4.8 Article

Highly functionalized pyranopyrans from furans: A synthesis of the C27-C38 and C44-C53 subunits of norhalichondrin B

Journal

ORGANIC LETTERS
Volume 9, Issue 25, Pages 5299-5302

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/ol702559e

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Funding

  1. NCI NIH HHS [CA 110246] Funding Source: Medline

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A synthesis of highly functionalized pyranopyrans based on an Achmatowicz oxidation followed by a remarkably diastereoselective Kishi reduction is described in the context of studies directed toward norhalichondrin B.

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