Journal
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
Volume 365, Issue 1861, Pages 2829-2843Publisher
ROYAL SOC
DOI: 10.1098/rsta.2007.0013
Keywords
adaptive optics; aberrations; confocal microscopy; multiphoton microscopy; optical data storage; optical tweezers
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Funding
- BBSRC [BB/E004946/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/E004946/1] Funding Source: researchfish
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The imaging properties of optical microscopes are often compromised by aberrations that reduce image resolution and contrast. Adaptive optics technology has been employed in various systems to correct these aberrations and restore performance. This has required various departures from the traditional adaptive optics schemes that are used in astronomy. This review discusses the sources of aberrations, their effects and their correction with adaptive optics, particularly in confocal and two-photon microscopes. Different methods of wavefront sensing, indirect aberration measurement and aberration correction devices are discussed. Applications of adaptive optics in the related areas of optical data storage, optical tweezers and micro/nanofabrication are also reviewed.
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