Journal
JOURNAL OF SURGICAL ONCOLOGY
Volume 96, Issue 8, Pages 671-677Publisher
WILEY
DOI: 10.1002/jso.20918
Keywords
colorectal micrometastases; sentinel node biopsy; prognostic markers
Funding
- NCI NIH HHS [CA090848] Funding Source: Medline
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The sentinel lymph node (SLN) technique has practical applications in multiple solid tumors including colorectal carcinoma. Identifying the SLN(s) provides better staging of the regional lymphatics beyond standard H&E analysis. This additional information assists in predicting biology and may be useful in guiding adjuvant therapy. We postulate the era of sentinel node has ushered in a new generation of node-negative patients; patients that have an exceptionally favorable outcome when compared to historic controls.
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