Journal
TETRAHEDRON LETTERS
Volume 48, Issue 51, Pages 9030-9034Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2007.10.067
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A combinatorial synthetic route yielding benzoxazoles and benzothiazoles is described. The use of o-halophenylisocyanides in the Ugi reaction (U-4CR) followed by a copper-catalyzed cyclization affords the benzoxazole as well as the benzothiazole moiety in good yield and high diversity. (c) 2007 Elsevier Ltd. All rights reserved.
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