4.6 Article

Association between number of siblings and cause-specific mortality in the Glasgow alumni cohort study

Journal

EUROPEAN JOURNAL OF EPIDEMIOLOGY
Volume 23, Issue 2, Pages 89-93

Publisher

SPRINGER
DOI: 10.1007/s10654-007-9210-6

Keywords

Siblings; childhood; cause-specific mortality; life course; early life exposures

Funding

  1. Medical Research Council [G106/1247] Funding Source: researchfish
  2. MRC [G106/1247] Funding Source: UKRI
  3. Medical Research Council [G106/1247] Funding Source: Medline

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In the Glasgow University Alumni cohort, students with no siblings experienced higher respiratory disease mortality. This risk diminished after accounting for potential confounders. We did not find strong evidence of an association with all cause, coronary heart disease, stroke or stomach cancer mortality. Number of siblings is a proxy for other exposures and exploring its association with specific disease outcomes can help disentangle some of the pathways relating early life exposures to adult mortality.

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