4.7 Review

Aptamers as molecular recognition elements for electrical nanobiosensors

Journal

ANALYTICAL AND BIOANALYTICAL CHEMISTRY
Volume 390, Issue 4, Pages 1023-1032

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s00216-007-1643-y

Keywords

aptamers; nanobiosensors; electrochemical aptamer sensors; field-effect transistor aptamer sensors

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Recent advances in nanotechnology have enabled the development of nanoscale sensors that outperform conventional biosensors. This review summarizes the nanoscale biosensors that use aptamers as molecular recognition elements. The advantages of aptamers over antibodies as sensors are highlighted. These advantages are especially apparent with electrical sensors such as electrochemical sensors or those using field-effect transistors.

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