Journal
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY
Volume 34, Issue 1, Pages 36-39Publisher
HUMANA PRESS INC
DOI: 10.1007/s12016-007-8029-y
Keywords
autoantibodies; Rheumatoid factor; Anti-cyclic citrullinated peptide; CCP2 test
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The literature of the last 4 years confirms that the anti-CCP2 test is a very useful marker for the early and specific diagnosis of rheumatoid arthritis (RA). The antiCCP2 test is very specific for RA (95-99%) and has sensitivity comparable to that of the rheumatoid factor (70-75%). The antibodies can be detected very early in the disease and can be used as an indicator for the progression and prognosis of RA. In this review, these interesting properties and some future possibilities of this diagnostic test are discussed.
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