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Neuroimaging Findings in Alcohol-Related Encephalopathies

Journal

AMERICAN JOURNAL OF ROENTGENOLOGY
Volume 195, Issue 6, Pages 1378-1384

Publisher

AMER ROENTGEN RAY SOC
DOI: 10.2214/AJR.09.4130

Keywords

alcohol abuse; alcohol withdrawal delirium; central pontine myelinolysis; extrapontine myelinolysis; hepatic encephalopathy; Marchiafava-Bignami disease; nervous system; Wernicke encephalopathy

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OBJECTIVE. Our aim was to review the emergent neuroimaging findings of alcohol-related CNS nontraumatic disorders. Alcohol (ethanol) promotes inflammatory processes, increases DNA damage, and creates oxidative stress. In addition, the accompanying thiamine deficiency may lead to Wernicke encephalopathy. Associated changes in serum osmolarity may lead to acute demyelination. CONCLUSION. Alcohol-related encephalopathies can be life-threatening conditions but can be prevented or treated, if recognized.

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