4.2 Article

Efficient synthesis of highly functionalized thiazolidine-4-ones under solvent-free conditions

Journal

MONATSHEFTE FUR CHEMIE
Volume 139, Issue 2, Pages 133-136

Publisher

SPRINGER WIEN
DOI: 10.1007/s00706-007-0751-x

Keywords

thiazolidine-4-one; 4-phenylthiosemicarbazide; heterocycle synthesis; solvent-free synthesis

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4-Phenylthiosemicarbazide reacts smoothly with dimethyl acetylenedicarboxylate in the presence of aldehydes or ketones under solvent free conditions to produce highly functionalized thiazolidine-4-ones.

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