Related references
Note: Only part of the references are listed.miR-21 regulates chronic hypoxia-induced pulmonary vascular remodeling
Shanzhong Yang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2012)
miR-210 has an antiapoptotic effect in pulmonary artery smooth muscle cells during hypoxia
Deming Gou et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2012)
Cyclic AMP response element-binding protein prevents endothelial permeability increase through transcriptional controlling p190RhoGAP expression
Koteswara Rao Chava et al.
BLOOD (2012)
Gremlin Plays a Key Role in the Pathogenesis of Pulmonary Hypertension
Edwina Cahill et al.
CIRCULATION (2012)
A Role for miR-145 in Pulmonary Arterial Hypertension Evidence From Mouse Models and Patient Samples
Paola Caruso et al.
CIRCULATION RESEARCH (2012)
A role for the CXCL12 receptor, CXCR7, in the pathogenesis of human pulmonary vascular disease
Christine M. Costello et al.
EUROPEAN RESPIRATORY JOURNAL (2012)
The MicroRNA-328 Regulates Hypoxic Pulmonary Hypertension by Targeting at Insulin Growth Factor 1 Receptor and L-Type Calcium Channel-α1C
Lei Guo et al.
HYPERTENSION (2012)
Elevated levels of hypoxia-inducible microRNA-210 in pre-eclampsia: new insights into molecular mechanisms for the disease
Yi Zhang et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2012)
Loss of the Oxygen Sensor PHD3 Enhances the Innate Immune Response to Abdominal Sepsis
Judit Kiss et al.
JOURNAL OF IMMUNOLOGY (2012)
Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia
Tobias Eckle et al.
NATURE MEDICINE (2012)
Antagonism of CXCR7 attenuates chronic hypoxia-induced pulmonary hypertension
Ecaterina Sartina et al.
PEDIATRIC RESEARCH (2012)
HIF and the Lung Role of Hypoxia-inducible Factors in Pulmonary Development and Disease
Larissa A. Shimoda et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)
Monocyte Chemoattractant Protein-1 Released from Alveolar Macrophages Mediates the Systemic Inflammation of Acute Alveolar Hypoxia
Jie Chao et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2011)
The HIF-1-Inducible Lysyl Oxidase Activates HIF-1 via the Akt Pathway in a Positive Regulation Loop and Synergizes with HIF-1 in Promoting Tumor Cell Growth
Floriane Pez et al.
CANCER RESEARCH (2011)
Early Macrophage Recruitment and Alternative Activation Are Critical for the Later Development of Hypoxia-Induced Pulmonary Hypertension
Eleni Vergadi et al.
CIRCULATION (2011)
Targeting of c-kit plus haematopoietic progenitor cells prevents hypoxic pulmonary hypertension
N. Gambaryan et al.
EUROPEAN RESPIRATORY JOURNAL (2011)
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice
Sarah R. Walmsley et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
An Intact Canonical NF-κB Pathway Is Required for Inflammatory Gene Expression in Response to Hypoxia
Susan F. Fitzpatrick et al.
JOURNAL OF IMMUNOLOGY (2011)
Hypoxia Potentiates MicroRNA-Mediated Gene Silencing through Posttranslational Modification of Argonaute2
Connie Wu et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
The novel chemokine receptor CXCR7 regulates trans-endothelial migration of cancer cells
Brian A. Zabel et al.
MOLECULAR CANCER (2011)
Ischemia and reperfusion-from mechanism to translation
Holger K. Eltzschig et al.
NATURE MEDICINE (2011)
Mechanisms of Disease: Hypoxia and Inflammation.
Holger K. Eltzschig et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Pulmonary Vascular Dysfunction Is Associated with Poor Outcomes in Patients with Acute Lung Injury
Todd M. Bull et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2010)
Dynamic Changes in Lung MicroRNA Profiles During the Development of Pulmonary Hypertension due to Chronic Hypoxia and Monocrotaline
Paola Caruso et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2010)
MicroRNA-210 A unique and pleiotropic hypoxamir
Stephen Y. Chan et al.
CELL CYCLE (2010)
Roles of Hypoxia-Inducible Factor-1α (HIF-1α) Versus HIF-2α in the Survival of Hepatocellular Tumor Spheroids
Heidi Menrad et al.
HEPATOLOGY (2010)
Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation
Hongxia Z. Imtiyaz et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice
Michele M. Hickey et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Hypoxia-Induced Mitogenic Factor (HIMF/FIZZ1/RELMα) Increases Lung Inflammation and Activates Pulmonary Microvascular Endothelial Cells via an IL-4-Dependent Mechanism
Kazuyo Yamaji-Kegan et al.
JOURNAL OF IMMUNOLOGY (2010)
Acute Hypoxia Induces HIF-Independent Monocyte Adhesion to Endothelial Cells through Increased Intercellular Adhesion Molecule-1 Expression: The Role of Hypoxic Inhibition of Prolyl Hydroxylase Activity for the Induction of NF-κB
Sandra Winning et al.
JOURNAL OF IMMUNOLOGY (2010)
CXCR7 Functions as a Scavenger for CXCL12 and CXCL11
Ulrike Naumann et al.
PLOS ONE (2010)
Sterile inflammation: sensing and reacting to damage
Grace Y. Chen et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMα) induces the vascular and hemodynamic changes of pulmonary hypertension
Daniel J. Angelini et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
Sustained hypoxia promotes the development of a pulmonary artery-specific chronic inflammatory microenvironment
Danielle L. Burke et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
L-Arginine promotes angiogenesis in the chronically hypoxic lung: a novel mechanism ameliorating pulmonary hypertension
K. Howell et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2009)
The Systemic Inflammation of Alveolar Hypoxia Is Initiated by Alveolar Macrophage-Borne Mediator(s)
Jie Chao et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2009)
Reactive Oxygen Species-generating Mitochondrial DNA Mutation Up-regulates Hypoxia-inducible Factor-1α Gene Transcription via Phosphatidylinositol 3-Kinase-Akt/Protein Kinase C/Histone Deacetylase Pathway
Nobuko Koshikawa et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Citrullination of CXCL12 Differentially Reduces CXCR4 and CXCR7 Binding with Loss of Inflammatory and Anti-HIV-1 Activity via CXCR4
Sofie Struyf et al.
JOURNAL OF IMMUNOLOGY (2009)
Adenosine A2A receptor is a unique angiogenic target of HIF-2α in pulmonary endothelial cells
Aftab Ahmad et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension
Christine M. Costello et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2008)
Hypoxia Selectively Activates the CREB Family of Transcription Factors in the In Vivo Lung
Martin O. Leonard et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2008)
Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure
Yoji Andrew Minamishima et al.
BLOOD (2008)
Anatomical and functional intrapulmonary shunt in acute respiratory distress syndrome
Massimo Cressoni et al.
CRITICAL CARE MEDICINE (2008)
Role of oxidative stress and NFkB in hypoxia-induced pulmonary edema
Sagi Sarada et al.
EXPERIMENTAL BIOLOGY AND MEDICINE (2008)
The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis
Eoin P. Cummins et al.
GASTROENTEROLOGY (2008)
Mucosal protection by hypoxia-inducible factor prolyl hydroxylase inhibition
Andreas Robinson et al.
GASTROENTEROLOGY (2008)
Hypoxia-inducible factor augments experimental colitis through an MIF-dependent inflammatory signaling cascade
Yatrik M. Shah et al.
GASTROENTEROLOGY (2008)
Inhibition of hypoxia inducible factor hydroxylases protects against renal ischemia-reperfusion injury
Peter Hill et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2008)
Hypoxia-induced IL-18 increases hypoxia-inducible factor-1α expression through a Rac1-dependent NF-κB pathway
Jeongki Kim et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
Jordi Rius et al.
NATURE (2008)
Deficiency or inhibition of oxygen sensor Phd1 induces hypoxia tolerance by reprogramming basal metabolism
Julian Aragones et al.
NATURE GENETICS (2008)
A2B adenosine receptor dampens hypoxia-induced vascular leak
Tobias Eckle et al.
BLOOD (2008)
Hypoxia up-regulates hypoxia-inducible factor-1α transcription by involving phosphatidylinositol 3-kinase and nuclear factor κB in pulmonary artery smooth muscle cells
Rachida S. BelAiba et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature
Zhenhua Miao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Alveolar macrophages are necessary for the systemic inflammation of acute alveolar hypoxia
Norberto C. Gonzalez et al.
JOURNAL OF APPLIED PHYSIOLOGY (2007)
Evidence that renal arterial-venous oxygen shunting contributes to dynamic regulation of renal oxygenation
Chai-Ling Leong et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2007)
Reactive oxygen species activate the HIF-1α promoter via a functional NFκB site
Steve Bonello et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2007)
Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo
Erinn B. Rankin et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Hypoxia-induced mitogenic factor has proangiogenic and proinflammatory effects in the lung via VEGF and VEGF receptor-2
Kazuyo Yamaji-Kegan et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2006)
Prolyl hydroxylase-1 negatively regulates IκB kinase-β, giving insight into hypoxia-induced NFκB activity
Eoin P. Cummins et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
Matthew E. Cockman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Translational control of collagen prolyl 4-hydroxylase-α(I) gene expression under hypoxia
Michael Faehling et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiology
Thomas G. Smith et al.
PLOS MEDICINE (2006)
Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-κB
Stilla Frede et al.
BIOCHEMICAL JOURNAL (2006)
Effects of partial ventilatory support modalities on respiratory function in severe hypoxemic lung injury
Dietrich Henzler et al.
CRITICAL CARE MEDICINE (2006)
Hypoxia-inducible factor prolyl 4-hydroxylase inhibition - A target for neuroprotection in the central nervous system
A Siddiq et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Inhibition of rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation
JM Hyvelin et al.
CIRCULATION RESEARCH (2005)
Hypoxia-induced neutrophil survival is mediated by HIF-1α-dependent NF-κB activity
SR Walmsley et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
The physiologic basis of high-altitude diseases
JB West
ANNALS OF INTERNAL MEDICINE (2004)
Hepatocyte growth factor-activated NF-κB regulates HIF-1 activity and ODC expression, implicated in survival, differently in different carcinoma cell lines
L Tacchini et al.
CARCINOGENESIS (2004)
Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats
T Nagaoka et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2004)
Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium:: Role of ectonucleotidases and adenosine A2B receptors
HK Eltzschig et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Tumor necrosis factor-α causes accumulation of a ubiquitinated form of hypoxia inducible factor-1α through a nuclear factor-κB-dependent pathway
J Zhou et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
Microtubule disruption utilizes an NFκB-dependent pathway to stabilize HIF-1α protein
YJ Jung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Chronic hypoxia causes angiogenesis in addition to remodelling in the adult rat pulmonary circulation
K Howell et al.
JOURNAL OF PHYSIOLOGY-LONDON (2003)
NF-κB plays a key role in hypoxia-inducible factor-1-regulated erythropoietin gene expression
YG Figueroa et al.
EXPERIMENTAL HEMATOLOGY (2002)
Involvement of a ferroprotein sensor in hypoxia-mediated inhibition of neutrophil apoptosis
KI Mecklenburgh et al.
BLOOD (2002)
The structural basis of pulmonary hypertension in chronic lung disease: remodelling, rarefaction or angiogenesis?
N Hopkins et al.
JOURNAL OF ANATOMY (2002)
FIH-1:: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
PC Mahon et al.
GENES & DEVELOPMENT (2001)
Transcriptional regulation by the phosphorylation-dependent factor CREB
B Mayr et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2001)
Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia
T Minamino et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
HIFα targeted for VHL-mediated destruction by proline hydroxylation:: Implications for O2 sensing
M Ivan et al.
SCIENCE (2001)
Permissive hypercapnia impairs pulmonary gas exchange in the acute respiratory distress syndrome
F Feihl et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)
Medical progress - The acute respiratory distress syndrome.
LB Ware et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)