4.6 Article

Deletion of Keap1 in the Lung Attenuates Acute Cigarette Smoke-Induced Oxidative Stress and Inflammation

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Nrf2-dependent sulfiredoxin-1 expression protects against cigarette smoke-induced oxidative stress in lungs

Anju Singh et al.

FREE RADICAL BIOLOGY AND MEDICINE (2009)

Article Biochemistry & Molecular Biology

Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress

C. J. Harvey et al.

FREE RADICAL BIOLOGY AND MEDICINE (2009)

Article Multidisciplinary Sciences

Targeting Nrf2 with the triterpenoid CDDO-imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

Thomas E. Sussan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Article Biochemistry & Molecular Biology

Distal airways in mice exposed to cigarette smoke - Nrf2-regulated genes are increased in Clara cells

Tracy L. Adair-Kirk et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Down-Regulated NF-E2-Related Factor 2 in Pulmonary Macrophages of Aged Smokers and Patients with Chronic Obstructive Pulmonary Disease

Masaru Suzuki et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2008)

Article Respiratory System

Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema

D. Goven et al.

THORAX (2008)

Review Respiratory System

Definition, epidemiology and natural history of COPD

G. Viegi et al.

EUROPEAN RESPIRATORY JOURNAL (2007)

Review Physiology

Pathobiology of cigarette smoke-induced chronic obstructive pulmonary disease

Toshinori Yoshida et al.

PHYSIOLOGICAL REVIEWS (2007)

Article Biochemistry & Molecular Biology

Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-imidazolide

Rajesh K. Thimmulappa et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Article Biochemistry & Molecular Biology

Glutathione peroxidase 2, the major cigarette smoke-inducible isoform of GPX in lungs, is regulated by Nrf2

Anju Singh et al.

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2006)

Article Medicine, General & Internal

Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer

Anju Singh et al.

PLOS MEDICINE (2006)

Article Biochemistry & Molecular Biology

Epithelial cell PPARγ contributes to normal lung maturation

Dawn M. Simon et al.

FASEB JOURNAL (2006)

Article Biochemistry & Molecular Biology

Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity

H Okawa et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)

Article Biochemistry & Molecular Biology

BTB protein keap1 targets antioxidant transcription factor nrf2 for ubiquitination by the cullin 3-Roc1 ligase

M Furukawa et al.

MOLECULAR AND CELLULAR BIOLOGY (2005)

Article Multidisciplinary Sciences

Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network

JY Sun et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate for proteasomal degradation of Nrf2

A Kobayashi et al.

MOLECULAR AND CELLULAR BIOLOGY (2004)

Article Biochemistry & Molecular Biology

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex

DD Zhang et al.

MOLECULAR AND CELLULAR BIOLOGY (2004)

Article Medicine, Research & Experimental

Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice

T Rangasamy et al.

JOURNAL OF CLINICAL INVESTIGATION (2004)

Review Biochemistry & Molecular Biology

Nrf2-Keap1 defines a physiologically important stress response mechanism

H Motohashi et al.

TRENDS IN MOLECULAR MEDICINE (2004)

Article Genetics & Heredity

Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

N Wakabayashi et al.

NATURE GENETICS (2003)

Article Biochemistry & Molecular Biology

Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene

JY Sun et al.

EMBO JOURNAL (2002)

Article Biochemical Research Methods

Site- and time-specific gene targeting in the mouse

D Metzger et al.

METHODS (2001)

Article Medicine, Research & Experimental

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

Y Kasahara et al.

JOURNAL OF CLINICAL INVESTIGATION (2000)

Review Medicine, General & Internal

Medical progress: Chronic obstructive pulmonary disease.

PJ Barnes

NEW ENGLAND JOURNAL OF MEDICINE (2000)

Article Critical Care Medicine

Oxidants/antioxidants and COPD

W MacNee

CHEST (2000)