4.7 Article

Targeting Phosphoinositide-3-Kinase-δ with Theophylline Reverses Corticosteroid Insensitivity in Chronic Obstructive Pulmonary Disease

Related references

Note: Only part of the references are listed.
Article Critical Care Medicine

Inhibition of PI3Kδ Restores Glucocorticoid Function in Smoking-induced Airway Inflammation in Mice

John A. Marwick et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2009)

Article Pharmacology & Pharmacy

Therapeutic potential of phosphatidylinositol 3-kinase inhibitors in inflammatory respiratory disease

Kazuhiro Ito et al.

JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)

Article Medicine, General & Internal

Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease

Peter M. A. Calverley et al.

NEW ENGLAND JOURNAL OF MEDICINE (2007)

Article Surgery

IGF-1 protects intestinal epithelial cells from oxidative stress-induced apoptosis

Naira Baregamian et al.

JOURNAL OF SURGICAL RESEARCH (2006)

Article Critical Care Medicine

Senescence marker protein-30 protects mice lungs from oxidative stress, aging, and smoking

Tadashi Sato et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2006)

Article Allergy

Phosphoinositide 3-kinase-δ inhibitor reduces vascular permeability in a murine model of asthma

Kyung Sun Lee et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2006)

Article Medicine, General & Internal

Decreased histone deacetylase activity in chronic obstructive pulmonary disease

K Ito et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Article Immunology

Theophylline restores histone deacetylase activity and steroid responses in COPD macrophages

BG Cosio et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2004)

Article Critical Care Medicine

Histone acetylase and deacetylase activity in alveolar macrophages and blood mononocytes in asthma

BG Cosío et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2004)

Review Respiratory System

Chronic obstructive pulmonary disease: molecular and cellular mechanisms

PJ Barnes et al.

EUROPEAN RESPIRATORY JOURNAL (2003)

Article Biochemistry & Molecular Biology

Selective role of PI3Kδ in neutrophil inflammatory responses

C Sadhu et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2003)

Article Critical Care Medicine

Impaired inhibition by dexamethasone of cytokine release by alveolar macrophages from patients with chronic obstructive pulmonary disease

SV Culpitt et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2003)

Article Biochemistry & Molecular Biology

Redox regulation of PI3K/Akt and p53 in bovine aortic endothelial cells exposed to hydrogen peroxide

K Niwa et al.

ANTIOXIDANTS & REDOX SIGNALING (2003)

Article Biochemistry & Molecular Biology

Regulation of histone deacetylase 2 by protein kinase CK2

SC Tsai et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Multidisciplinary Sciences

A molecular mechanism of action of theophylline: Induction of histone deacetylase activity to decrease inflammatory gene expression

K Ito et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Critical Care Medicine

Effect of theophylline on induced sputum inflammatory indices and neutrophil chemotaxis in chronic obstructive pulmonary disease

SV Culpitt et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2002)