Journal
JOURNAL OF MATHEMATICAL BIOLOGY
Volume 56, Issue 3, Pages 347-371Publisher
SPRINGER HEIDELBERG
DOI: 10.1007/s00285-007-0118-2
Keywords
vesicle membrane; lipid bilayer; multi-component membrane; open membrane; phase field model; diffuse interface model; numerical simulation
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Diffuse interface (phase field) models are developed for multi-component vesicle membranes with different lipid compositions and membranes with free boundary. These models are used to simulate the deformation of membranes under the elastic bending energy and the line tension energy with prescribed volume and surface area constraints. By comparing our numerical simulations with recent biological experiments, it is demonstrated that the diffuse interface models can effectively capture the rich phenomena associated with the multi-component vesicle transformation and thus offering great functionality in their simulation and modelling.
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