Journal
BIOTECHNOLOGY LETTERS
Volume 30, Issue 3, Pages 441-444Publisher
SPRINGER
DOI: 10.1007/s10529-007-9578-0
Keywords
astaxanthin; direct extraction; green process; Haematococcus pluvialis; vegetable oil
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Funding
- National Research Foundation of Korea [2006-06557, 16-2008-05-002-00] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
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A green, downstream process using common vegetable oils was used for the direct extraction of astaxanthin from Haematococcus. The process consists of a single integrated unit to extract astaxanthin with subsequent separation of the astaxanthin-containing oil extract. Without a cell harvest process step, the culture broth was directly mixed with the vegetable oils; the astaxanthin inside the cell was extracted into the vegetable oil phase by hydrophobic interactions, with recovery yields of 88% and above. The oil extracts were simply separated from the culture medium containing cell debris by gravity settling only.
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