Journal
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
Volume 63, Issue 6, Pages 601-610Publisher
WILEY
DOI: 10.1111/j.1600-0897.2010.00852.x
Keywords
Abortion; cytokine network; implantation; preterm labor; reproduction
Categories
Ask authors/readers for more resources
T-helper (Th) cells play a central role in modulating immune responses. The Th1/Th2 paradigm has now developed into the new Th1/Th2/Th17 paradigm. In addition to effector cells, Th cells are regulated by regulatory T (Treg) cells. Their capacity to produce cytokines is suppressed by immunoregulatory cytokines such as transforming growth factor (TGF)-beta and interleukin (IL)-10 or by cell-to-cell interaction. Here, we will review the immunological environment in normal pregnancy and complicated pregnancy, such as implantation failure, abortion, preterm labor, and preeclampsia from the viewpoint of the new Th1/Th2/Th17 and Treg paradigms.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available