Journal
AMERICAN JOURNAL OF PUBLIC HEALTH
Volume 103, Issue -, Pages 133-135Publisher
AMER PUBLIC HEALTH ASSOC INC
DOI: 10.2105/AJPH.2012.301208
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Funding
- National Institutes of Health [1R01ES020447-01, R21 MH094688-01]
- Tulane University (Clinical and Translational Research and Education Center)
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We examined the association between telomere length and prenatal tobacco exposure (PTE) in 104 children aged 4 to 14 years. Salivary telomere length (STL) was determined from salivary DNA using quantitative polymerase chain reaction. Of the children, 18% had maternal reported PTE. Mean STL was significantly lower among children with PTE (6.4 vs 7.5, P < .05). Findings extend the literature demonstrating the negative long-term effects of PTE to include a cellular marker of aging linked to multiple negative health outcomes.
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