Journal
EPIDEMIOLOGY AND INFECTION
Volume 136, Issue 5, Pages 621-627Publisher
CAMBRIDGE UNIV PRESS
DOI: 10.1017/S095026880700917X
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Funding
- National Institutes of Health, USA
- National Health and Medical Research Council of Australia
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We undertook a 5-year retrospective study of group A streptococcal (GAS) bacteraemia in Fiji, Supplemented by a 9-month detailed retrospective study of beta-haemolytic streptococcal (BHS) infections. The all-age incidence of GAS bacteraemia over 5 years was 11 center dot 6/100 000. Indigenous Fijians were 4 center dot 7 times more likely to present with invasive BHS disease than people of other ethnicities, and 6 center dot 4 times more likely than Indo-Fijians. The case-fatality rate For invasive BHS infections was 28%. emm-typing was performed on 23 isolates: 17 different emm-types were Found, and the emm-type profile was different from that found in industrialized nations. These data support the contentions that elevated rates of invasive BHS and GAS infections are widespread in developing countries, and that the profile of invasive organisms in these settings reflects a wide diversity of emm-types and a paucity of types typically found in Industrialized countries.
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