Related references
Note: Only part of the references are listed.Beyond triglyceride synthesis: the dynamic functional roles of MGAT and DGAT enzymes in energy metabolism
Yuguang Shi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Intestinal lipid absorption
Jahangir Iqbal et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Phosphatidate degradation: Phosphatidate phosphatases (lipins) and lipid phosphate phosphatases
David N. Brindley et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2009)
Molecular Mechanisms of Hepatic Steatosis and Insulin Resistance in the AGPAT2-Deficient Mouse Model of Congenital Generalized Lipodystrophy
Victor A. Cortes et al.
CELL METABOLISM (2009)
Phosphatidic Acid Phosphatase, a Key Enzyme in the Regulation of Lipid Synthesis
George M. Carman et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Lipin proteins and metabolic homeostasis
Karen Reue et al.
JOURNAL OF LIPID RESEARCH (2009)
This month in the journal
Robin E. Williamson
AMERICAN JOURNAL OF HUMAN GENETICS (2008)
Association of a polymorphism in the lipin 1 gene with systolic blood pressure in men
K. L. Ong et al.
AMERICAN JOURNAL OF HYPERTENSION (2008)
Acute effects of insulin on the activity of mitochondrial GPAT1 in primary adipocytes
Gennady E. Bronnikov et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Evaluating the role of LPIN1 variation in insulin resistance, body weight, and human lipodystrophy in UK populations
Katherine A. Fawcett et al.
DIABETES (2008)
Phosphatidic acid mediates demyelination in Lpin1 mutant mice
Karim Nadra et al.
GENES & DEVELOPMENT (2008)
AGPAT6 is a novel microsomal glycerol-3-phosphate acyltransferase
Yan Qun Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Temporal and Spatial Regulation of the Phosphatidate Phosphatases Lipin 1 and 2
Neil Grimsey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Lipin1 Is a Key Factor for the Maturation and Maintenance of Adipocytes in the Regulatory Network with CCAAT/Enhancer-binding Protein α and Peroxisome Proliferator-activated Receptor γ2
Yoo-Kyung Koh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Adipose tissue lipin-1 expression is correlated with peroxisome proliferator-activated receptor alpha gene expression and insulin sensitivity in healthy young men
Jimmy Donkor et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2008)
Regulation of lipin-1 gene expression by glucocorticoids during adipogenesis
Peixiang Zhang et al.
JOURNAL OF LIPID RESEARCH (2008)
Thematic review series: Glycerolipids - Mammalian glycerol-3-phosphate acyltransferases: new genes for an old activity
Ruth E. Gimeno et al.
JOURNAL OF LIPID RESEARCH (2008)
Glucocorticoids and cyclic AMP selectively increase hepatic lipin-1 expression, and insulin acts antagonistically
Boripant Manmontri et al.
JOURNAL OF LIPID RESEARCH (2008)
Multiple roles for lipins/phosphatidate phosphatase enzymes in lipid metabolism
Karen Reue et al.
JOURNAL OF LIPID RESEARCH (2008)
Identification of a novel sn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient in Agpat6-/- mice
Cynthia A. Nagle et al.
JOURNAL OF LIPID RESEARCH (2008)
DGAT enzymes and triacylglycerol biosynthesis
Chi-Liang Eric Yen et al.
JOURNAL OF LIPID RESEARCH (2008)
LPIN1 genetic variation is associated with rosiglitazone response in type 2 diabetic patients
Eun Seok Kang et al.
MOLECULAR GENETICS AND METABOLISM (2008)
The lipin protein family: Dual roles in lipid biosynthesis and gene expression
Karen Reue et al.
FEBS LETTERS (2008)
Mammalian acyl-CoA:lysophosphatidylcholine acyltransferase enzymes
Eric Soupene et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Genetic variants within the LPIN1 gene, encoding lipin, are influencing phenotypes of the metabolic syndrome in humans
Silke Wiedmann et al.
DIABETES (2008)
The cellular functions of the yeast lipin homolog pah1p are dependent on its phosphatidate phosphatase activity
Gil-Soo Han et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
LPIN2 is associated with type 2 diabetes, glucose metabolism, and body composition
Yurii S. Aulchenko et al.
DIABETES (2007)
Association of Lipin 1 gene polymorphisms with measures of energy and glucose metabolism
Ruth J. F. Loos et al.
OBESITY (2007)
Cloning and functional characterization of a novel mitochondrial N-ethylmaleimide-sensitive glycerol-3-phosphate acyltransferase (GPAT2)
Shuli Wang et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2007)
Topology of acyltransferase motifs and substrate specificity and accessibility in 1-acyl-sn-glycero-3-phosphate acyltransferase 1
Atsushi Yamashita et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2007)
Hepatic lipin 1β expression is diminished in insulin-resistant obese subjects and is reactivated by marked weight loss
Michelle A. Croce et al.
DIABETES (2007)
Lipodystrophies: Windows on adipose biology and metabolism
Robert A. Hegele et al.
JOURNAL OF LIPID RESEARCH (2007)
Functional characterization of human 1-acylglycerol-3-phosphate-O-acyltransferase isoform 9:: cloning, tissue distribution, gene structure, and enzymatic activity
Anil K. Agarwal et al.
JOURNAL OF ENDOCRINOLOGY (2007)
Hepatic overexpression of glycerol-sn-3-phosphate acyltransferase 1 in rats causes insulin resistance
Cynthia A. Nagle et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The small molecule harmine is an antidiabetic cell-type-specific regulator of PPARγ expression
Hironori Waki et al.
CELL METABOLISM (2007)
Increased oxidative stress is associated with balanced increases in hepatocyte apoptosis and proliferation in glycerol-3-phosphate acyltransferase-1 deficient mice
Linda E. Hammond et al.
EXPERIMENTAL AND MOLECULAR PATHOLOGY (2007)
Molecular cloning of a murine glycerol-3-phosphate acyltransferase-like protein 1 (xGPAT1)
Nagakatsu Harada et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2007)
Novel aspects of PPARα-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study
Pascal G. P. Martin et al.
HEPATOLOGY (2007)
Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns
Jimmy Donkor et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
A splice site mutation confirms the role of LPIN2 in Majeed syndrome
Zakiya S. Al-Mosawi et al.
ARTHRITIS AND RHEUMATISM (2007)
Efficacy and safety of leptin-replacement therapy and possible mechanisms of leptin actions in patients with generalized lipodystrophy
Ken Ebihara et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2007)
The liver X receptor (LXR) and hepatic lipogenesis - The carbohydrate-response element-binding protein is a target gene of LXR
Ji-Young Cha et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Insulin controls subcellular localization and multisite phosphorylation of the phosphatidic acid phosphatase, lipin 1
Thurl E. Harris et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
A role of lipin in human obesity and insulin resistance: relation to adipocyte glucose transport and GLUT4 expression
Vanessa van Harmelen et al.
JOURNAL OF LIPID RESEARCH (2007)
Molecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis
Jingsong Cao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Lipin deficiency impairs diurnal metabolic fuel switching
Jun Xu et al.
DIABETES (2006)
Roles of phosphatidate phosphatase enzymes in lipid metabolism
George M. Carman et al.
TRENDS IN BIOCHEMICAL SCIENCES (2006)
Antileukemic activity of lysophosphatidic acid acyltransferase-β inhibitor CT32228 in chronic myelogenous leukemia sensitive and resistant to imatinib
Paul La Rosee et al.
CLINICAL CANCER RESEARCH (2006)
Hepatic knockdown of mitochondrial GPAT1 in ob/ob mice improves metabolic profile
Haiyan Xu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
Lipin expression is attenuated in adipose tissue of insulin-resistant human subjects and increases with peroxisome proliferator-activated receptor γ activation
Aiwei Yao-Borengasser et al.
DIABETES (2006)
Lysophosphatidic acid acyltransferase-β (LPAAT-β) is highly expressed in advanced ovarian cancer and is associated with aggressive histology and poor survival
Catherine S. M. Diefenbach et al.
CANCER (2006)
Lipin 1 is an inducible amplifier of the hepatic PGC-1α/PPARα regulatory pathway
Brian N. Finck et al.
CELL METABOLISM (2006)
Effect of lysophosphatidic acid acyltransferase-β inhibition in acute leukemia
Michael G. Douvas et al.
LEUKEMIA RESEARCH (2006)
Identification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cells
Xueni Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Cloning and characterization of mouse lung-type acyl-CoA: Lysophosphatidylcholine acyltransferase 1 (LPCAT1) - Expression in alveolar type II cells and possible involvement in surfactant production
Hiroki Nakanishi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The C-terminal region of mitochondrial glycerol-3-phosphate acyltransferase-1 interacts with the active site region and is required for activity
Magali Pellon-Maison et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2006)
Functional characterization of human 1-acylglycerol-3-phosphate acyltransferase isoform 8: Cloning, tissue distributions gene structure, and enzymatic activity
Anil K. Agarwal et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2006)
A regulatory role for 1-acylglycerol-3-phosphate-O-acyltransferase 2 in adipocyte differentiation
SE Gale et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
The Saccharomyces cerevisiae lipin homolog is a Mg2+-dependent phosphatidate phosphatase enzyme
GS Han et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Agpat6 deficiency causes subdermal lipodystrophy and resistance to obesity
L Vergnes et al.
JOURNAL OF LIPID RESEARCH (2006)
Agpat6 -: a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium
AP Beigneux et al.
JOURNAL OF LIPID RESEARCH (2006)
Liver-directed overexpression of mitochondrial glycerol-3-phosphate acyltransferase results in hepatic steatosis, increased triacylglycerol secretion and reduced fatty acid oxidation
Daniel Linden et al.
FASEB JOURNAL (2006)
Substrate specificity of lysophosphatidic acid acyltransferase β -: evidence from membrane and whole cell assays
D Hollenback et al.
JOURNAL OF LIPID RESEARCH (2006)
Cross-species analyses implicate Lipin 1 involvement in human glucose metabolism
E Suviolahti et al.
HUMAN MOLECULAR GENETICS (2006)
Genetic basis of lipodystrophies and management of metabolic complications
AK Agarwal et al.
ANNUAL REVIEW OF MEDICINE (2006)
Phenotypic heterogeneity in biochemical parameters correlates with mutations in AGPAT2 or Seipin genes among Berardinelli-Seip congenital lipodystrophy patients
KB Gomes et al.
JOURNAL OF INHERITED METABOLIC DISEASE (2005)
Expression and regulation of 1-acyl-sn-glycerol-3-phosphate acyltransferases in the epidermis
B Lu et al.
JOURNAL OF LIPID RESEARCH (2005)
Lysophosphatidic acid acyltransferase-β is a prognostic marker and therapeutic target in gynecologic malignancies
GM Springett et al.
CANCER RESEARCH (2005)
Cloning and characterization a novel human 1-acyl-sn-glycerol-3-phosphate acyltransferase gene AGPAT7
GM Ye et al.
DNA SEQUENCE (2005)
Alternatively spliced lipin isoforms exhibit distinct expression pattern, subcellular localization, and role in adipogenesis
M Péterfy et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs
LE Hammond et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Induction of apoptosis using inhibitors of lysophosphatidic acid acyltransferase-β and anti-CD20 monoclonal antibodies for treatment of human non-Hodgkin's lymphomas
JM Pagel et al.
CLINICAL CANCER RESEARCH (2005)
Prevention of hepatic steatosis and hepatic insulin resistance in mitochondrial acyl-CoA:glycerol-sn-3-phosphate acyltransferase 1 knockout mice
S Neschen et al.
CELL METABOLISM (2005)
Homozygous mutations in LPIN2 are responsible for the syndrome of chronic recurrent multifocal osteomyelitis and congenital dyserythropoietic anaemia (Majeed syndrome)
PJ Ferguson et al.
JOURNAL OF MEDICAL GENETICS (2005)
Genome-wide expression analysis reveals 100 adrenal gland-dependent circadian genes in the mouse liver
Katsutaka Oishi et al.
DNA RESEARCH (2005)
Expression of lysophosphatidic acid acyltransferase beta (LPAAT-β) in ovarian carcinoma:: correlation with tumour grading and prognosis
S Niesporek et al.
BRITISH JOURNAL OF CANCER (2005)
Mitochondrial glycerol-3-phosphate acyltransferase-1 directs the metabolic fate of exogenous fatty acids in hepatocytes
TM Lewin et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)
Molecular characterization of PS-341 (bortezomib) resistance:: implications for overcoming resistance using lysophosphatidic acid acyltransferase (LPAAT)-β inhibitors
T Hideshima et al.
ONCOGENE (2005)
Enzymatic activity of naturally occurring 1-acylglycerol-3-phosphate-O-acyltransferase 2 mutants associated with congenital generalized lipodystrophy
W Haque et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Cloning and characterization of murine 1-acyl-sn-glycerol 3-phosphate acyltransferases and their regulation by PPARα in murine heart
B Lu et al.
BIOCHEMICAL JOURNAL (2005)
Identification of a new glycerol-3-phosphate acyltransferase isoenzyme, mtGPAT2, in mitochondria*
TM Lewin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Enzymes of triacylglycerol synthesis and their regulation
RA Coleman et al.
PROGRESS IN LIPID RESEARCH (2004)
Lipid phosphate phosphatases and related proteins: Signaling functions in development, cell division, and cancer
DN Brindley
JOURNAL OF CELLULAR BIOCHEMISTRY (2004)
A novel cardiolipin-remodeling pathway revealed by a gene encoding an endoplasmic reticulum-associated acyl-CoA:lysocardiolipin acyltransferase (ALCAT1) in mouse
JS Cao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Lipin expression preceding peroxisome proliferator-activated receptor-γ is critical for adipogenesis in vivo and in vitro
J Phan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Overexpression of mitochondrial GPAT in rat hepatocytes leads to decreased fatty acid oxidation and increased glycerolipid biosynthesis
D Lindén et al.
JOURNAL OF LIPID RESEARCH (2004)
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
SH Lecker et al.
FASEB JOURNAL (2004)
Phenotypic and genetic heterogeneity in congenital generalized lipodystrophy
AK Agarwal et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
Cloning and identification of the human LPAAT-zeta gene, a novel member of the lysophosphatidic acid acyltransferase family
D Li et al.
JOURNAL OF HUMAN GENETICS (2003)
Congenital generalized lipodystrophy: significance of triglyceride biosynthetic pathways
AK Agarwal et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2003)
Phenotypic heterogeneity in body fat distribution in patients with congenital generalized lipodystrophy caused by mutations in the AGPAT2 or Seipin genes
V Simha et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2003)
Mitochondrial glycerol-3-phosphate acyltransferase-deficient mice have reduced weight and liver triacylglycerol content and altered glycerolipid fatty acid composition
LE Hammond et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
Coordinated transcription of key pathways in the mouse by the circadian clock
S Panda et al.
CELL (2002)
AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome 9q34
AK Agarwal et al.
NATURE GENETICS (2002)
Leptin-replacement therapy for lipodystrophy
EA Oral et al.
NEW ENGLAND JOURNAL OF MEDICINE (2002)
Insulin-stimulated phosphorylation of lipin mediated by the mammalian target of rapamycin
TA Huffman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
ATP-independent fatty acyl-coenzyme A synthesis from phospholipid -: Coenzyme A-dependent transacylation activity toward lysophosphatidic acid catalyzed by acyl-coenzyme A:lysophosphatidic acid acyltransferase
A Yamashita et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Analysis of the structure, substrate specificity, and mechanism of squash glycerol-3-phosphate (1)-acyltransferase
AP Turnbull et al.
STRUCTURE (2001)
Overexpression of 1-acyl-glycerol-3-phosphate acyltransferase-α enhances lipid storage in cellular models of adipose tissue and skeletal muscle
H Ruan et al.
DIABETES (2001)
Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin
M Peterfy et al.
NATURE GENETICS (2001)
Share Paper
