4.6 Article

Transcorneal Suture Fixation of Posterior Lamellar Grafts in Eyes With Minimal or Absent Iris-Lens Diaphragm

Journal

AMERICAN JOURNAL OF OPHTHALMOLOGY
Volume 151, Issue 3, Pages 460-464

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.ajo.2010.08.043

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Funding

  1. PFIZER (UK)
  2. Fondazione Banca degli Occhi del Veneto (Venice, Italy)

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PURPOSE: To describe a technique that uses a transcorneal suture for safe delivery and fixation of donor tissue during Descemet stripping automated endothelial keratoplasty in patients that are at risk of graft dislocation into the vitreous cavity as a result of minimal or absent iris lens diaphragm. DESIGN: Interventional case series. METHODS: Thirteen eyes with endothelial decompensation and inadequate iris lens diaphragm underwent modified Descemet stripping automated endothelial keratoplasty surgery. A 10-0 Prolene suture (Ethicon Inc) was passed through the endothelial graft and used to pull the graft into the eye and anchor it onto the recipient cornea. Best-corrected visual acuity, refraction, and complications were recorded. RESULTS: Preoperative best-corrected visual acuity was less than 20/200 in all cases. Eleven patients had a pre-existing comorbidity (glaucoma, n = 8; previous retinal detachment, n = 2; epiretinal membrane n = 1). Average follow-up was 11.3 months (range, 3 to 36 months). No graft dislocation occurred during surgery. After surgery, graft detachment was noted in 2 cases and rebubbling succeeded in achieving reattachment. All patients had successful attachment of the endothelial graft. Postoperative best-corrected visual acuity improved in 11 of 13 patients and remained unchanged in 2 patients. CONCLUSIONS: In patients with insufficient iris lens diaphragm, this technique allowed safe graft delivery, prevented intraoperative and postoperative graft dislocation, and facilitated successful rebubbling in case of postoperative graft detachment. (Am J Ophthalmol 2011;151:460-464. (C) 2011 by Elsevier Inc. All rights reserved.)

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