Journal
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
Volume 198, Issue 2, Pages -Publisher
MOSBY-ELSEVIER
DOI: 10.1016/j.ajog.2007.06.057
Keywords
diet; epidemiology; infertility; ovulation; protein
Categories
Funding
- NCI NIH HHS [U01 CA067262, R01 CA065725, R01 CA067262, P01 CA055075, CA55075, CA67262, CA67883, R01 CA050385-18, CA65725, CA50385, R01 CA067883, R01 CA050385] Funding Source: Medline
- NHLBI NIH HHS [HL64108, R01 HL064108, HL03804] Funding Source: Medline
- NIA NIH HHS [AG/CA14742] Funding Source: Medline
- NICHD NIH HHS [L50 HD056672-01, L50 HD056672] Funding Source: Medline
- NIDDK NIH HHS [T32 DK007703-13, DK52866, T32 DK007703, T32 DK-007703] Funding Source: Medline
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OBJECTIVE: The objective of the study was to evaluate whether intake of protein from animal and vegetable origin is associated with ovulatory infertility. STUDY DESIGN: A total of 18,555 married women without a history of infertility were followed up as they attempted a pregnancy or became pregnant during an 8 year period. Dietary assessments were related to the incidence of ovulatory infertility. RESULTS: During follow-up, 438 women reported ovulatory infertility. The multivariate-adjusted relative risk (RR) (95% confidence interval [CI]; P for trend) of ovulatory infertility comparing the highest to the lowest quintile of animal protein intake was 1.39 (1.01 to 1.90; 0.03). The corresponding RR (95% CI; P for trend) for vegetable protein intake was 0.78 (0.54 to 1.12; 0.07). Furthermore, consuming 5% of total energy intake as vegetable protein rather than as animal protein was associated with a more than 50% lower risk of ovulatory infertility (P =.007). CONCLUSION: Replacing animal sources of protein with vegetable sources of protein may reduce ovulatory infertility risk.
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