Journal
VASCULAR HEALTH AND RISK MANAGEMENT
Volume 4, Issue 4, Pages 769-774Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/VHRM.S955
Keywords
microparticles; flow cytometry; techniques
Categories
Ask authors/readers for more resources
Although long considered to be cellular debris, microparticles (MPs) are more recently considered reflective of cellular stimulation, activation, and degeneration/apoptosis. MPs that arise from the cellular components of blood and the endothelial lining of blood vessels are referred to as blood MPs and by general consensus are small (<= 1.5 mu m ), expose the anionic phospholipid (PL) phosphatidylserine (PS) on the outer leafl et of their membrane, and bear surface membrane antigens reflecting their cellular origin. This brief review summarizes the different approaches used by several groups to study blood MPs. The aim of this article is to review the technical aspects of characterizing the morphological and functional properties of blood MPs with emphasis on the preanalytical and analytical variables involved in these studies.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available