Journal
AMERICAN JOURNAL OF NEURORADIOLOGY
Volume 31, Issue 5, Pages 856-861Publisher
AMER SOC NEURORADIOLOGY
DOI: 10.3174/ajnr.A2005
Keywords
-
Ask authors/readers for more resources
BACKGROUND AND PURPOSE. Imaging studies have shown that children with NF-1 have increased brain volumes compared with age-matched controls and the CCs are disproportionately large The purpose of this study was to determine if the CC in adults with NF-1 differed from that in matched controls by using DTI and volumetric imaging MATERIALS AND METHODS MR imaging with DTI was performed in 10 adults with NF-1 and in 10 age-, sex-, and handedness-matched controls by using a 3T system Total brain volumes and the areas and central lengths of the CC were calculated, along with the radial width of callosal subdivisions, in the 2 groups RESULTS Our results showed that the total brain volume was not significantly different between adults with NF-1 and matched controls The length and total cross-sectional area of the CC were statistically larger in adults with NF-1 compared with controls (approximately 10% longer and 20% greater area) On DTI we found a preservation of the primary eigenvalue with increases in the minor eigenvalues at tne genu CONCLUSIONS. We have shown that the increased size of the CC found in children with NF-1 is also present in adults with the syndrome, whereas no difference in total brain volume was found
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available