4.5 Article

Immediate Anatomic Results after the Endovascular Treatment of Ruptured Intracranial Aneurysms: Analysis in the CLARITY Series

Journal

AMERICAN JOURNAL OF NEURORADIOLOGY
Volume 31, Issue 5, Pages 907-911

Publisher

AMER SOC NEURORADIOLOGY
DOI: 10.3174/ajnr.A1954

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Funding

  1. Boston Scientific France

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BACKGROUND AND PURPOSE The efficacy of the endovascular treatment in providing stable occlusion of intracranial aneurysms is still controversial and should be precisely analyzed A first step is to carefully study immediate anatomical results CLARITY (Clinical and Anatomical Results in the Treatment of Ruptured Intracranial Aneurysms) is a prospective multicenter consecutive series including patients treated by coiling for ruptured aneurysms Immediate anatomic results are presented MATERIALS AND METHODS. Postoperative anatomic results were evaluated by DSA by the treating physician and anonymously and independently by 2 experienced neuroradiologrsts by using the 3-point Montreal Scale Patients were divided into 2 groups patients treated with GDC and those treated with Matrix detachable coils RESULTS A total of 773 patients 1461 women, 312 men, 19-80 years of age, mean, 51 2 +/- 132 years) with 773 ruptured aneurysms were included in the study The rate of occlusion as determined by the treating physician was designated complete for 586 aneurysms (75 8%), neck remnant for 145 aneurysms 118 8%), and aneurysm remnant for 42 aneurysms 15 4%) The same evaluation as reported by the 2 independent reviewers was complete occlusion for 366 aneurysms (47 4%), neck remnant for 324 aneurysms 141 9%), and aneurysm remnant for 83 aneurysms (10 7%) Postoperative anatomic results were significantly linked to age but not to the technique of endovascular treatment or aneurysm characteristics (location, size, dome-to neck ratio) Results were not significantly different between the GDC and Matrix group CONCLUSIONS Endovascular treatment of ruptured intracranial aneurysms resulted in a high rate of satisfactory occlusion (complete occlusion and neck remnant in 89 3%) Patient age was the only factor associated with the rate of occlusion The rate of aneurysm occlusion differed insignificantly between GDC and Matrix coils

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