Journal
AMERICAN JOURNAL OF MEDICINE
Volume 124, Issue 6, Pages 489-497Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.amjmed.2011.01.015
Keywords
Cardiovascular risk; Endothelial progenitor cells; Stem cells
Categories
Funding
- Austrian Society of Cardiology
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Since the discovery of endothelial progenitor cells in 1997, the scientific world has seen their ups and downs. There has been much discussion about the detection methods of endothelial progenitor cells and their diagnostic and predictive value. A lack of standardized methods to define endothelial progenitor cells has led to a number of nomenclatures and measuring methods that are difficult for clinicians to oversee. Therefore, only specialized hematologists and cardiologists were aware of their existence. Now it is time for a change: Most of the controversies have been eliminated by elaborate studies. This review aims to give an overview to the clinically working physician about the measurement, diagnostic potential, predictive value, and therapeutic potential of endothelial progenitor cells. (C) 2011 Elsevier Inc. All rights reserved. The American Journal of Medicine (2011) 124, 489-497
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