Journal
AMERICAN JOURNAL OF KIDNEY DISEASES
Volume 53, Issue 6, Pages 1068-1081Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1053/j.ajkd.2009.02.012
Keywords
Residual kidney function; hemodialysis; peritoneal dialysis; dialysis adequacy; preservation; survival
Categories
Funding
- Kidney Foundation of Canada Biomedical Fellowship
Ask authors/readers for more resources
Increasing the dialysis dose has failed to have an impact on the mortality of dialysis patients. In contrast, residual kidney function (RKF) has consistently been a potent predictor of improved survival for both hemodialysis and peritoneal dialysis patients. The benefits of RKF preservation challenge historical concepts of dialysis adequacy that have focused principally on achieving small-solute clearance targets. In this review, we highlight the evidence supporting the impact of RKF on survival and quality of life of dialysis patients and provide a mechanistic framework for this relationship. Current strategies to preserve RKF also are reviewed, emphasizing those used in patients treated with peritoneal dialysis. Am J Kidney Dis 53:1068-1081. (C) 2009 by the National Kidney Foundation, Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available