4.5 Article

Patients with Acinetobacter baumannii bloodstream infections are colonized in the gastrointestinal tract with identical strains

Journal

AMERICAN JOURNAL OF INFECTION CONTROL
Volume 38, Issue 9, Pages 751-753

Publisher

MOSBY-ELSEVIER
DOI: 10.1016/j.ajic.2010.03.005

Keywords

Acinetobacter baumannii; hospital epidemiology

Funding

  1. University of Maryland General Clinical Research Center [M01 RR 16500]
  2. General Clinical Research Centers Program
  3. National Center for Research Resources (NCRR)
  4. National Institutes of Health [R01 AI60859-01A1, 1K24AI079040-01A1, 1K12RR023250-03]
  5. University of Maryland Internal Funds

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In this study, we identified critically ill patients with Acinetobacter baumannii bacteremia and examined perirectal surveillance cultures for the presence of genetically related A baumannii strains using pulsed-field gel electrophoresis to determine whether gut colonization preceded clinical infection. Seven patients with imipenem-resistant A baumannii bacteremia were identified from January to June of 2008. Six of 7 (86%) patients were colonized in the gastrointestinal tract with genetically similar strains preceding their bacteremia.

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