Journal
AMERICAN JOURNAL OF HUMAN GENETICS
Volume 82, Issue 1, Pages 10-18Publisher
CELL PRESS
DOI: 10.1016/j.ajhg.2007.12.001
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Funding
- NATIONAL HUMAN GENOME RESEARCH INSTITUTE [Z01HG200325, ZIAHG200325] Funding Source: NIH RePORTER
- Intramural NIH HHS Funding Source: Medline
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An astonishing amount of behavioral variation is captured within the more than 350 breeds of dog recognized worldwide. Inherent in observations of dog behavior is the notion that much of what is observed is breed specific and will persist, even in the absence of training or motivation. Thus, herding, pointing, tracking, hunting, and so forth are likely to be controlled, at least in part at the genetic level. Recent studies in canine genetics suggest teat small numbers of genes control major morphologic phenotypes. By extension, we hypothesize that at least some canine behaviors will also be controlled by small numbers of genes that can be readily mapped. In this review, we describe our current understanding of a representative subset of canine behaviors, as well as approaches for phenotyping, genome-wide scans, and data analysis. Finally, we discuss the applicability of studies of canine behavior to human genetics.
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