Journal
AMERICAN JOURNAL OF GASTROENTEROLOGY
Volume 113, Issue 10, Pages 1437-1439Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1038/s41395-018-0237-y
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Funding
- Birmingham NIHR Biomedical Research Centre based in the University Hospitals Birmingham NHS Foundation Trust
- University of Birmingham
- Wellcome trust
- Core Digestive Diseases Charity
- PSC
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Understanding the role of modest alcohol consumption in patients with non-alcohol induced fatty liver disease (NAFLD) remains a significant challenge, with no clear guidance on counselling regarding alcohol use. Conventionally, the strong association of alcohol excess and development of complications related to chronic liver disease, including hepatocellular carcinoma, has led practitioners to advocate complete abstinence to those with NAFLD. New evidence published in this issue of the Red Journal challenges the historic paradigm by showing that modest, nonbinge wine consumption (< 70 g/week) associates with significantly lower risk of advanced hepatic fibrosis on biopsy compared with complete abstinence across a well-characterised single centre cohort of nearly 200 patients with NAFLD.
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