Journal
AMERICAN JOURNAL OF GASTROENTEROLOGY
Volume 104, Issue 10, Pages 2617-2624Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ajg.2009.440
Keywords
-
Categories
Funding
- Seed Funding Program for Basic Research of the University of Hong Kong [200711159034]
Ask authors/readers for more resources
Fibrolamellar hepatocellular carcinoma (FHLCC) generally occurs in young individuals lacking a background of chronic liver disease and other risk factors for hepatocellular carcinoma. The clinical presentations of FLHCC are generally nonspecific, and the alpha-fetoprotein level is typically within the normal range in most cases. Imaging studies have a major role in clinical diagnosis, but pathology is the gold standard in confirming diagnosis. Pathological characteristics of FLHCC include the presence of tumor cells with a deeply eosinophilic cytoplasm and macronucleoli surrounded by abundant fibrous bands. The most effective treatment for FLHCC is aggressive surgical resection. This comprehensive literature review gives a full account of the clinical, pathological, and molecular features of FLHCC.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available