Journal
AMERICAN JOURNAL OF CLINICAL PATHOLOGY
Volume 137, Issue 1, Pages 132-141Publisher
AMER SOC CLINICAL PATHOLOGY
DOI: 10.1309/AJCPQX1KBJ2PZJFK
Keywords
Diagnostic testing; Test methods; Diagnostic accuracy studies; Fine-needle aspiration; Cytology; Test performance variation; Test conditions; Test parameters; Reporting quality
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Diagnostic test accuracy (DTA) studies on fine-needle aspiration cytology (FNAC) often show considerable variability in diagnostic accuracy between study centers. Many factors affect the accuracy of FNAC. A complete description of the testing parameters would help make valid comparisons between studies and determine causes of performance variation. We investigated the manner in which test conditions are specified in FNAC DTA studies to determine which parameters are most commonly specified and the frequency with which they are specified and to see whether there is significant variability in reporting practice. We identified 17 frequently reported test parameters and found significant variation in the reporting of these test specifications across studies. On average, studies reported 5 of the 17 items that would be required to specify the test conditions completely. A more complete and standardized reporting of methods, perhaps by means of a checklist, would improve the interpretation of FNAC DTA studies.
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