Journal
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH
Volume 53, Issue -, Pages 419-425Publisher
WILEY
DOI: 10.1111/j.1365-2788.2009.01158.x
Keywords
atherosclerosis; congenital heart defect; Down syndrome; pulmonary arterial hypertension; thyroid-related cardiac impairment; trisomy 21
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This review focuses on the heart and vascular system in patients with Down syndrome. A clear knowledge on the wide spectrum of various abnormalities associated with this syndrome is essential for skilful management of cardiac problems in patients with Down syndrome. Epidemiology of congenital heart defects, cardiovascular aspects and thyroid-related cardiac impairment in patients with Down syndrome will be discussed.
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