Journal
NATURE REVIEWS CANCER
Volume 9, Issue 5, Pages 371-377Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/nrc2604
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Funding
- National Institutes of Health [GM083303]
- American Cancel Society California Division, Pamela
- Edward Taft Postdoctoral Fellowhip
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Cells living in a complex environment must constantly detect, process and appropriately respond to changing signals. Therefore, all cellular information processing is dynamic in nature. As a consequence. understanding the process of signal transduction often requires detailed quantitative analysis of dynamic behaviours. Here, we focus on the oscillatory dynamics of the tumour suppressor protein p53 as a model for studying protein dynamics in single cells to better understand its regulation and function.
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