Journal
ALLERGY AND ASTHMA PROCEEDINGS
Volume 30, Issue 4, Pages 397-405Publisher
OCEAN SIDE PUBLICATIONS INC
DOI: 10.2500/aap.2009.30.3256
Keywords
Allergic rhinitis; cedar; cypress; double-blind study; foodstuff; immunomodulator; Lactobacillus paracasei strain KW3110; pollinosis; preventative effect; probiotics; treatment
Categories
Funding
- Ministry of Health, Labor and Welfare
Ask authors/readers for more resources
Japanese cedar pollinosis is an important contributor to allergic rhinitis in Japan. Lactobacillus, may be useful as an immunomodulator and is used widely as a foodstuff. The purpose of the study was to examine the effects of daily intake of the Lactobacillus paracasei strain KW3110 in patients with cedar pollinosis. The effects of daily intake of KW3110 in patients with cedar pollinosis were investigated in 126 patients who received KW3110 or a placebo in a double-blind study. The study began I month before the start of the pollen season and lasted for 3 months. A significant reduction of nasal symptoms and the serum level of eosinophil cationic protein and improvement of quality of life scores occurred in the patients who received KW3110 when pollen scattering was low. However, the effects were limited during the peak period of pollen scattering. Intake of KW3110 may reduce allergic inflammation, but the effect is limited. (Allergy Asthma Proc 30:397-405, 2009; doi: 10.2500/aap.2009.30.3256)
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available