Journal
AKTUELLE RHEUMATOLOGIE
Volume 38, Issue 3, Pages 177-179Publisher
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0032-1327626
Keywords
chloroquine; rheumatoid arthritis; psychotic mania
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Chloroquine, an anti-malarial drug, is also used in the treatment of rheumatoid arthritis. It has been known for decades that chloroquine could cause psychiatric side effects; however, reports are scarce. This report concerns a rare case of 2 challenge and re-challenge episodes of mania during chloroquine treatment of rheumatoid arthritis. Some hypothetical pathophysiological mechanisms that may lead to these adverse effects are discussed.
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