Journal
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
Volume 74, Issue -, Pages 218-223Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.ijbiomac.2014.11.031
Keywords
In situ synthesis; Collagen-hydroxyapatite/pectin composite; Bone repairing material
Funding
- Doctoral Scientific Research of Henan University of Science and Technology [40221348009]
- National Natural Science Foundation of China [51373158, U1404824]
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Pectin, a kind of plant polysaccharide, was introduced into collagen-hydroxyapatite composite system, and prepared collagen-hydroxyapatite/pectin (Col-HA/pectin) composite in situ. The structure of the composite was investigated by XRD, SEM, and FT-IR. The mechanical properties, water absorption, enzyme degradation, and cytotoxicity of the composite were investigated as well. The results show that the inorganic substance in the composite materials is hydroxyapatite in relatively low crystallinity. A new interface appeared by the interaction among hydroxyapatite and collagen-pectin, and formed smooth fine particles. The mechanical properties, water absorption, enzyme degradation, and cytotoxicity indicate a potential use in bone replacement for the new composite. (C) 2014 Elsevier B.V. All rights reserved.
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