Journal
AIDS
Volume 24, Issue 7, Pages 1069-1072Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/QAD.0b013e328337fe01
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Funding
- Infectious Disease Clinical Research Program (IDCRP) [IDCRP-RV168F]
- Department of Defense (DoD)
- National Institute of Allergy and Infectious Diseases, National Institutes of Health (NIH) [Y1-AI-5072]
- N.F.C.C.
- B.K.A
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To assess the effect of obesity on CD4 cell counts, we estimated the association of time-updated BMI categories with CD4 changes among 1001 documented HIV seroconverters. During the pre-highly active antiretroviral therapy (HAART) era, a higher BMI was associated with less reduction in CD4 cell counts over time. However during the HAART era, obese versus normal weight patients had smaller increases in CD4 cell counts (+69 versus +116 cells, P=0.01). Lower CD4 cell counts may now be another adverse consequence of obesity.
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