Journal
AIDS
Volume 22, Issue 14, Pages 1699-1703Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/QAD.0b013e3283021a61
Keywords
HIV vaccine; protective immunity; recombinant viral vectors; T cells
Categories
Funding
- European Union
- Dutch AIDS Fund
- LSBR
- UMC Utrecht
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In September 2007, it was announced that the most promising HIV vaccine trial had to be stopped because it had failed to show the protection that was hoped for. Here, the history of HIV vaccine development from the discovery of HIV-1 in 1983 until 2008, the underlying ideas on protective immunity to HIV and potential avenues for vaccine research are discussed. (C) 2008 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
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