Journal
AICHE JOURNAL
Volume 54, Issue 12, Pages 3048-3067Publisher
WILEY
DOI: 10.1002/aic.11610
Keywords
biomaterials; tissue engineering; drug delivery; polymer scaffolds; hydrogels; biomimetics; bioreactors
Categories
Funding
- National Institutes of Health
- National Science Foundation
- NASA
- Whitaker Foundation
- Rice University Institute of Biosciences and Bioengineering through the Biotechnology Training [T32 GM008362]
- National Institute of General Medical Sciences [T32 GM007330]
Ask authors/readers for more resources
The need for techniques to facilitate the regeneration of failing or destroyed tissues remains great with the aging of the worldwide population and the continued incidence of trauma and diseases such as cancer. A 16-year history in biomaterial scaffold development and tissue engineering is examined, beginning with the synthesis of novel materials and fabrication of 3D porous scaffolds. Exploring cell-scaffold interactions and subsequently cellular delivery using biomaterial carriers, we have developed a variety of techniques for bone and cartilage engineering. In addition to delivering cells, we have utilized growth factors, DNA, and peptides to improve the in vitro and in vivo regeneration of tissues. This review covers important developments and discoveries within our laboratory, and the increasing breadth in the scope of our work within the expanding field of tissue engineering is presented. (C) 2008 American Institute of Chemical Engineers AIChE J, 54: 3048-3067, 2008
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available