Journal
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
Volume 45, Issue 6, Pages 662-666Publisher
ELSEVIER
DOI: 10.1016/j.ijantimicag.2015.01.020
Keywords
Dental implant components; Disinfection; Biofilm; Antimicrobial susceptibility
Funding
- UK Department of Health's National Institute for Health Research Biomedical Research Centres
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Biofilm development on the internal surfaces of dental implants and dental implant components may be associated with peri-implant hard and soft tissue abnormalities. Currently, no protocols have been established for effective disinfection of removable implant components. The purpose of this study was to evaluate the antibiofilm properties of commonly used dental antimicrobial agents (chlorhexidine and delmopinol) on multispecies biofilms. Biofilms of 48 h and 168 h maturity were exposed to 0.2% chlorhexidine, 2% chlorhexidine and a product containing 0.2% delmopinol for 5, 10 and 20 min. 2% chlorhexidine was the most effective agent, achieving a total viable biofilm reduction ranging from 96.2% to >99.99% depending on the time of exposure and the stage of biofilm development. (C) 2015 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.
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