Journal
AGING-US
Volume 2, Issue 10, Pages 735-741Publisher
IMPACT JOURNALS LLC
DOI: 10.18632/aging.100209
Keywords
EMT; senescence; cancer; Twist; Zeb1
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The epithelial-mesenchymal transition is involved in several physiological processes. However, it is also believed to contribute to cancer progression. Conversely, cellular senescence constitutes a failsafe program against cancer progression. Interestingly, EMT and senescence seem to cross paths, with several factors playing dominant roles in both settings. Here, we describe recent observations that link these important cellular processes.
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