4.7 Article

Oseltamivir-Resistant Influenza A Pandemic (H1N1) 2009 Virus, Hong Kong, China

Journal

EMERGING INFECTIOUS DISEASES
Volume 15, Issue 12, Pages 1970-1972

Publisher

CENTERS DISEASE CONTROL
DOI: 10.3201/eid1512.091057

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Funding

  1. Providence Foundation Limited
  2. Research Grants Council of the Hong Kong Special Administrative Region [7500/06M]
  3. Research Fund for the Control of Infectious Diseases of the Food and Health Bureau of the Hong Kong Government
  4. The University of Hong Kong
  5. Clinical Infectious Diseases Research Endowment Fund

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Resistance to oseltamivir was observed in influenza A pandemic (H1N1) 2009 virus isolated from an untreated person in Hong Kong, China. Investigations showed a resistant virus with the neuraminidase (NA) 274Y genotype in quasi-species from a nasopharyngeal aspirate. Monitoring for the naturally occurring NA 274Y mutation in this virus is necessary.

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