Journal
EMERGING INFECTIOUS DISEASES
Volume 15, Issue 12, Pages 2013-2016Publisher
CENTERS DISEASE CONTROL
DOI: 10.3201/eid1512.090194
Keywords
-
Categories
Funding
- European Network of Excellence NeuroPrion [FOOD-CT-2004-506579]
- Scottish National Blood Transfusion Services
- Chief Scientist Office of the Scottish Government [CZB/4/357]
- Department of Health
- Scottish Government
- Biotechnology and Biological Sciences Research Council [BBS/E/D/05241340, BBS/E/D/05241338] Funding Source: researchfish
- Medical Research Council [G0600953, G0900580] Funding Source: researchfish
- BBSRC [BBS/E/D/05241340, BBS/E/D/05241338] Funding Source: UKRI
- MRC [G0900580, G0600953] Funding Source: UKRI
Ask authors/readers for more resources
To assess interspecies barriers to transmission of transmissible spongiform encephalopathies (TSEs), we investigated the ability of disease-associated prion proteins (PrP(d)) to initiate conversion of the human normal cellular form of prion protein of the 3 major PRNP polymorphic variants in vitro. Protein misfolding cyclic amplification showed that conformation of PrP(d) partly determines host susceptibility.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
