4.7 Article

Recombination in Vaccine and Circulating Strains of Porcine Reproductive and Respiratory Syndrome Viruses

Journal

EMERGING INFECTIOUS DISEASES
Volume 15, Issue 12, Pages 2032-2035

Publisher

CENTERS DISEASE CONTROL
DOI: 10.3201/eid1512.090390

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Funding

  1. 973 Project [2005CB523200]
  2. Key Technology Research and Development Program [2007BAD86B02/04/06]
  3. National Natural Science Foundation of China [30770082, 30871871]
  4. Huazhong Agricultural University, Wuhan, China

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EM2007, a porcine reproductive and respiratory syndrome virus (PRRSV) variant with a unique 68 aa deletion in Nsp2, was recently isolated in China. Phylogenetic and molecular evolutionary analyses indicated that Em2007 is a natural recombinant between a vaccine strain of PRRSV and circulating virus. We also tested its pathogenicity in piglets.

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