Journal
ADVANCES IN COLLOID AND INTERFACE SCIENCE
Volume 207, Issue -, Pages 14-31Publisher
ELSEVIER
DOI: 10.1016/j.cis.2013.10.012
Keywords
Nanoparticles; Polymer architecture; Assembly; Layer-by-layer; Drug delivery; Nanotechnology
Categories
Funding
- Australian Research Council [120100030]
- Australian Research Council Super Science Fellowship [FS110200025]
- University of Melbourne
- Alexander von Humboldt Foundation
- [130101846]
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Hollow polymer capsules are attracting increasing research interest due to their potential application as drug delivery vectors, sensors, biomimetic nano- or multi-compartment reactors and catalysts. Thus, significant effort has been directed toward tuning their size, composition, morphology, and functionality to further their application. In this review, we provide an overview of emerging techniques for the fabrication of polymer capsules, encompassing: self-assembly, layer-by-layer assembly, single-step polymer adsorption, bio-inspired assembly, surface polymerization, and ultrasound assembly. These techniques can be applied to prepare polymer capsules with diverse functionality and physicochemical properties, which may fulfill specific requirements in various areas. In addition, we critically evaluate the challenges associated with the application of polymer capsules in drug delivery systems. (C) 2013 Elsevier B.V. All rights reserved.
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